Is it possible to take ibuprofen tablets during pregnancy. Ibuprofen. Instructions for use. Indications and side effects. Ibuprofen during pregnancy. Ibuprofen and alcohol. Damage to the central and peripheral nervous system

Every girl dreams of becoming a mother. The period of pregnancy in her life is associated with something: amazing, unforgettable, amazing. But, do not forget that it was at this time that a woman is incredibly responsible not only for herself, but also for the unborn child. Based on this, pregnant women need to be very careful and try to avoid negative external influences. A woman who gives birth not for the first time knows that immunity weakens and you can catch a cold any day, even if you are a little blown away. That is why it is important to know how to treat a cold.

Action of ibuprofen during pregnancy

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID / NSAID) that belongs to the group of propionic acid derivatives. The drug is a bright white powdery crystals, which is practically insoluble in water, but perfectly soluble in ethanol or acetone. Release form of the drug: tablets, syrup, gel, cream, ointment.

Ibuprofen has the following properties:

  1. Relieves inflammation, pain, eliminates fever.
  2. Stops or eliminates the biosynthesis of prostaglandins E and F, which provoke contraction of the muscle tissue of the uterus and gastrointestinal tract.
  3. It stimulates the production of special proteins that are secreted by the body when a viral infection - interferons - gets into it, therefore it perfectly supports the immune system and protects the body.
  4. The properties of the substance that eliminate pain and heat are more pronounced than the properties that eliminate inflammation. But ibuprofen works better than aspirin and amidopyrine, and has fewer negative effects than more NSAIDs.

Ibuprofen is on the WHO List of Essential Medicines. The application is practiced by doctors from all over the world.

Is ibuprofen possible during pregnancy: when is it prescribed

Pregnancy is not without complications in the majority of the fairer sex. However, no person is 100% healthy and everyone can catch a cold. And the health of the child also depends on the condition of the woman during gestation, therefore, the therapy of many pathologies is performed by doctors with the help of the most effective medication that is not harmful to the baby developing in the womb. However, one cannot but say that treatment with serious medications is carried out only in the most severe cases, when the potential harm to the child is less than that caused to the health of a pregnant woman.

So, Ibuprofen and medications with it are prescribed:

  1. To stop acute pain, as well as for the treatment of diseases of the musculoskeletal system: arthrosis, arthritis, inflammatory processes resulting from injury.
  2. For headaches and pain in the teeth, as a pain reliever.
  3. At high temperatures as a heat reliever.
  4. During the period of acute respiratory infections, to maintain the immune system in the fight against pathologies and to relieve inflammation in the ears, nasopharynx, larynx.
  5. As an alternative to antibacterial agents for mild disease.
  6. As a replacement for Aspirin, because Ibuprofen does not inhibit blood clotting and does not provoke bleeding.

Attention! Self-administration of drugs is contraindicated during pregnancy.

Is Ibuprofen used during early pregnancy?

Doctors often allow drinking or using Ibuprofen topically when the first and second trimester of pregnancy is in progress. Because it has been proven that the drug cannot have any negative impact on the development of the baby during this period. But, very careful use of Ibuprofen in any form should be in the very early stages of bearing a child. In the first twelve weeks, the drug can be dangerous for the baby, in principle, like any other medication (MIG, Ibuklin, Nurofen, Ibufen, etc.).

During this period, all:

  • Fabrics;
  • Systems;
  • Organs of the child.

Impact on a developing small organism chem. substances is highly undesirable. Studies have been carried out and scientists have found that Ibuprofen and other medications of the NSAID class increase the risk of miscarriage by 2.4 times. Of the more than 4500 miscarriages studied, 352 (7.5%) women were treated with non-aspirin NSAIDs.

Experts have come to the conclusion that the use of any dosage of NSAIDs for women in the early stages of gestation greatly increases the risk of spontaneous abortion.

In the third trimester (after 28 weeks), Ibuprofen is not recommended. The medicine has a direct effect on the process of uterine contraction, cervical ripening, childbirth. There is a risk of miscarriage or premature birth.

Ibuprofen ointment during pregnancy: 1 trimester

It is not uncommon for a pregnant woman to suffer from a joint disease and in the first trimester the pathology worsens, or the woman injured the ligaments. However, there is no need to drink pills often; it is better to replace them with external topical agents.

Today, there is almost no difference between ointments and gels based on the main active ingredient.

They do not differ significantly in the speed of absorption and in the constituent components. After application to the skin, the therapeutic effect occurs as soon as the active substance is absorbed.

Having penetrated the inflamed area, the ointment:

  • Affects the painful area;
  • Reduces pain syndrome quickly;
  • Eases the condition of a woman.

But some part of the drug still enters the woman's bloodstream. Ibuprofen is readily absorbed into the placenta. Although the concentration of the active substance in the blood for external use is several times less than if you drink a couple of tablets, this should be taken into account. We must not forget that if the drug in the 1st trimester is relatively safe for a developing baby, it should not be abused, one way or another. A pregnant woman may face a common side effect of NSAIDs - a negative effect on the gastric mucosa. And this can lead to the development of gastritis or even ulcers.

In this case, you should rebuild the diet and follow a special diet.

In the early stages, a pregnant woman should eat, which is said for two. It can be quite difficult to follow such a diet for stomach diseases. This negative result usually comes from taking tablets or suspensions. Parenteral administration (injections) are the least dangerous in this regard, but after them inflammation may develop at the site of the needle entry. A sore stomach or inflammation at the injection site can lead to the appointment of other medications that are no longer as safe for the child in the early stages than Ibuprofen.

As statistics show, the appointment of Ibuprofen for systemic use is required in approximately 5% of all carrying a child registered in the clinic. Therefore, despite the fact that the drug is seemingly harmless, in the first trimester it should be used only according to indications, as prescribed by the attending physician.

2nd trimester: Ibuprofen during pregnancy

It is possible to use the drug in the 2nd trimester only as directed by a doctor, but the drug can cause side effects.

The reaction of a pregnant woman's body to Ibuprofen may be as follows:

  • Nausea and vomiting;
  • Pain in the gastrointestinal tract;
  • Bleeding;
  • Allergy of various manifestations;
  • Insomnia;
  • Visual impairment;
  • Instability of the psyche, irritability, apathy;
  • Hallucinations (rarely, in case of overdose);
  • Feeling of lack of oxygen, rapid breathing.

If you take the medicine once, you can hardly be afraid of side effects, but during therapy with a course, they can appear at any time. The longer the course of therapy with Ibuprofen lasts, the greater the likelihood of side effects.

3rd trimester: Ibuprofen during pregnancy

Particularly dangerous for the development of the child is the use of the medication during gestation in the third trimester. The time when it is absolutely impossible to use Ibuprofen is the 3rd trimester. All drug studies show a strong effect of this active ingredient on the baby. At this stage of pregnancy, it is better to avoid all medications altogether, since most of the drugs can penetrate into the blood of the expectant mother, and therefore through the placenta to the baby.

What is possible to replace the drug with? Ibuprofen belongs to the group of NSAID medications, which also includes other active ingredients. The safest of these is paracetamol. Among the medicines that do not have the strongest effect on the fetus, it is worth mentioning Paracetamol and Papaverine.

These are medications such as:

  • No-Shpa;
  • Panadol;
  • Drotaverinum.

They have a mild effect and will help relieve pain of moderate intensity, as well as reduce the manifestations of the inflammatory process and bring down high temperatures. Temperature is very harmful when carrying a child, sometimes even more than the medications themselves. Sometimes doctors do not recommend taking medications at all, but advise using alternative medicine methods. But, if the catarrhal pathology is serious and you cannot do without the help of medicines, then the doctor prescribes the most sparing therapy for the mother and child.

How to use Ibuprofen ointment for pregnant women (video)

In recent years, ibuprofen has been gaining in popularity during pregnancy. Is it as safe and as effective as the manufacturers say?

In the past, acetylsalicylic acid, or aspirin, was quite common during pregnancy. After its teratogenic effect was proven (that is, it was proved that taking aspirin can cause fetal malformations if taken early), the question arose about an alternative drug. And it is no coincidence, because the risk to which the fetus is exposed to respiratory viral infections is very high!

Ibuprofen is one such drug.

Ibuprofen is a non-steroidal anti-inflammatory drug (non-steroidal, which means non-hormonal). It is used mainly for the treatment of diseases of the musculoskeletal system - arthrosis, arthritis, inflammation that arose after injuries, as well as radiculitis, neuralgia. It can also be used to reduce pain during inflammatory processes in the ENT organs, adnexitis, algodismenorrhea (painful menstruation), with headache and toothache.

Recently, ibuprofen has also been used as an antipyretic agent.

The danger of a single use of ibuprofen during pregnancy is practically zero, which makes it the drug of choice for relieving acute pain or fever.

However, even in this case, you should consult your doctor before using ibuprofen, as the drug may be contraindicated in the patient for other reasons.

The main contraindications include, first of all, erosion and ulcers of the gastrointestinal tract in the stage of exacerbation, hematopoiesis disorders, the presence of the so-called "aspirin triad" (aspirin intolerance, bronchial asthma and nasal polyps), serious kidney and liver dysfunctions.

Ibuprofen is used with caution in later stages due to the fact that it suppresses the production of prostaglandins, and thereby affects uterine contractility and cervical maturation, as well as the generic dominant. Simply put, it can cause both premature birth and, with a greater degree of probability, overmaturity, and of course, abnormalities of labor. + to this there is a negative effect on the coagulation system of the mother and an increased risk of bleeding ..

In the first two trimesters, ibuprofen during pregnancy can be used if the danger of its use is less than the danger of the disease itself, but in the first trimester, the danger of taking it is still higher, since the organs and systems of the child are being formed.

In general, this is one of the safest antipyretic drugs for pregnant women, but it is worth remembering that this is a short-term rather than constant use ..

Ibuprofen is used in different dosage forms - from tablets to ointments, but it should be remembered that contraindications for use relate to the drug, and not to the form of its release. So ibuprofen ointment during pregnancy in the third trimester is as prohibited as syrups and tablets.

You should be aware that prolonged use of ibuprofen can exacerbate long-healed gastritis, gastric ulcer and duodenal ulcer, and can also provoke gastrointestinal bleeding, especially in people who have had episodes of similar bleeding in the past. The side effects of using ibuprofen during pregnancy include various disorders of the wasps of the digestive system - nausea, vomiting, upset stools, also allergic reactions (and quite severe - urticaria, Quincke's edema), disorders of the hematopoietic organs, kidney function. Headaches, sleep disturbances, dizziness, visual disturbances are possible.

All of these should be considered before using ibuprofen in pregnancy, and your doctor can best take these into account.

Ibuprofen is an anti-inflammatory nonsteroidal drug. It contains a substance of the same name, which has an analgesic, anti-inflammatory and antipyretic effect. Whether it can be taken by pregnant women with a cold, we will consider further.

Composition and form of the drug

The active ingredient of the drug is ibuprofen. The amount of active substance is determined depending on the form of drug release:

It is worth remembering that the following contraindications and side effects relate directly to the drug itself, and not to the form of its release.

Is Ibuprofen allowed during pregnancy?

Continuous use of the drug is contraindicated in the 1st and 3rd trimester of pregnancy, since there is a possibility of miscarriage, the development of congenital and gene mutations. The active substance of the drug penetrates the fetus, as a result of which it can cause the development of a large number of various congenital pathologies. It is not excluded:

  • increased uterine contractility;
  • the onset of premature birth, accompanied by serious complications.

Moreover, long-term use of the drug can provoke an exacerbation of previously healed gastritis, stomach and duodenal ulcers, in the most severe cases, gastrointestinal bleeding opens.

Regular intake of Ibuprofen can be prescribed during the 2nd trimester of pregnancy to eliminate severe pain and normalize body temperature. But all actions must be agreed with the doctor, otherwise there is a risk of causing serious harm to the fetus.

A single dose of Ibuprofen during pregnancy is practically not dangerous, therefore it is used to relieve acute pain or a rapid drop in temperature.

In general, Ibuprofen is one of the safest antipyretic drugs allowed during childbearing, but we are talking only about short-term, but not regular use.

Indications for taking Ibuprofen

As a rule, this remedy is prescribed for the following purposes:

  • For the treatment of various types of rheumatoid diseases, as well as deforming osteoarthritis. The most effective treatment for rheumatoid arthritis will be if the therapy is carried out in the early stages of the development of the disease - before there is a serious change in the joints.
  • As an antipyretic for the symptomatic treatment of fever provoked by infectious diseases.
  • For the treatment of migraines, pain after injury, surgery or toothache.

In some cases, Ibuprofen is taken during labor to slow labor activity and to relieve pain.

Mode of application

Regarding the method of application, the drug is used for oral use strictly after meals, thereby minimizing the negative impact on the state of the gastrointestinal tract. A single dosage is 1 tablet. It is forbidden to take more than 3 pieces per day.

To enhance the effect of treatment, the dosage can be increased, but only after consulting a specialist. The maximum daily dose is 1200 mg (6 tablets). When noticeable improvements appear, the dosage is gradually reduced.

In cases where the drug is prescribed during the treatment of rheumatoid arthritis and implies a long-term use, the expectant mother should constantly come for an examination to a specialist.

Contraindications

Ibuprofen has certain contraindications, which include:

  • the presence of hypersensitivity to the main active ingredient of the drug;
  • "Aspirin" asthma;
  • violation of blood clotting (in particular, poor blood clotting with a risk of bleeding);
  • the presence of erosive diseases of the gastrointestinal tract;
  • severe disruption of the liver and kidneys.

Ibuprofen therapy is carried out with extreme caution if there are problems in the work of the heart.

Side effects

The use of this drug for a fairly long period of time is strictly prohibited because of the potential for side effects. But in some cases, even a single dose can provoke the appearance of side effects, after the development of which the drug is canceled.

Side effects from Ibuprofen include:

  • the appearance of an allergic reaction (for example, hives, etc.);
  • disorder of the functioning of the digestive system - vomiting, nausea, stool disorder.

In some cases, this drug results in a severe headache that does not go away for a long time. Sleep disturbance occurs, there is a possibility of kidney dysfunction.

The likelihood that taking Ibuprofen will cause side effects is highest in the 3rd trimester of pregnancy.

What drugs can replace Ibuprofen?

The pharmacy has various non-steroidal anti-inflammatory drugs, among which the complete analogues of Ibuprofen are:

  • Ibufen
  • MIG 400
  • Faspik
  • Burana

If these drugs are not available, they can be replaced with drugs such as No-Shpa, Paracetamol (Panadol).

Video: Ibuprofen at 29 months pregnant

In the next video, the specialist will tell you whether a one-time dose of the drug during pregnancy is safe, and why all non-steroidal anti-inflammatory drugs are not recommended in the third trimester:

Taking Ibuprofen during the period of gestation should be done very carefully and only after consulting a specialist. Thanks to this approach, the expectant mother can protect herself and her child from negative consequences and complications. Even in cases where the doctor prescribes this remedy, its reception should not be longer than 2-3 days.

Ibuprofen is a non-steroidal anti-inflammatory drug. On sale you can find different forms of drugs based on it - tablets, ointments, gels, syrups. Ibuprofen helps to eliminate acute pain, cope with the symptoms of diseases of the musculoskeletal system, and normalizes body temperature in case of fever. It is often taken to relieve toothache and headache, discomfort that occurs with angina, otitis media, pharyngitis.

Since ibuprofen has a pronounced anti-inflammatory effect, in some cases it is prescribed instead of antibacterial drugs. Let's see if Ibuprofen can be taken during pregnancy.

Ibuprofen is an effective anti-inflammatory drug

Ibuprofen and pregnancy

Taking Ibuprofen during early pregnancy should only be done on the recommendation of a doctor. It is believed that in the first and second trimester, the medicine cannot change the normal course of fetal development, but still, in the first twelve obstetric weeks, when vital organs are laid, gynecologists recommend refraining from using drugs that contain ibuprofen. After all, a chemical effect on the mother's body during this period is extremely undesirable.

In addition, there is scientific evidence that all NSAIDs increase the risk of miscarriage by about 2.4 times. And Ibuprofen belongs to this category of drugs.

Thus, 4,705 cases of spontaneous abortions were studied. Of these, 352 (that is, more than 7%) are associated with the intake of NSAIDs by a pregnant woman. Given this information, the scientists concluded that the use of NSAIDs in the first trimester significantly increases the risk of spontaneous abortion. Therefore, despite the fact that the annotation to Ibuprofen does not prohibit drinking it in the early stages of pregnancy, many doctors refuse to prescribe such treatment to their patients.

FDA Safety Assessment for Ibuprofen

The FDA is the United States Food and Drug Administration. When researching pharmaceutical products, specialists of this structure classify drugs into several categories, taking into account how dangerous they are for the unborn child.

Ibuprofen is categorized by the FDA as a Category B. Class B can mean one of two things:

  • studies on pregnant animals were conducted and did not show that the drug negatively affects the fetus, and tests with pregnant women were not carried out;
  • Studies in pregnant animals have shown that the drug can adversely affect the fetus, but in testing in humans, the risks to the fetus have not been confirmed.

But this information only applies to taking Ibuprofen in the first two trimesters of pregnancy.


Drug research

For the third trimester, researchers categorized Ibuprofen as Category D, meaning it is dangerous to the fetus. The fact is that this drug affects the contractility of the uterus, labor and the rate of maturation of the cervix. Against the background of his admission, childbirth may begin ahead of time, or, on the contrary, the woman will postpone the child and then childbirth will have to be stimulated. Both situations negatively affect the health of the mother and child.

Thus, it is strictly forbidden to take the described medicine only in the last three months of pregnancy (from 29 to 40 (42) obstetric week).

How to replace ibuprofen during pregnancy

All medicines containing Ibuprofen can be taken in the first two trimesters only with the permission of a doctor if the expected benefit for the expectant mother outweighs the possible risks of the fetus. At a temperature, headache, a woman can take Paracetamol. It is considered safer for both mom and baby.


Paracetamol is a worthy alternative to Ibuprofen during gestation

How to take ibuprofen during pregnancy - dosages

For pregnant women, if necessary, Ibuprofen is prescribed in a standard dosage intended for adults, that is, one 200 mg tablet three to four times a day or one 400 mg tablet 2 times a day. In no case should the maximum permissible daily dose exceed 1200 mg, that is, six 200 mg tablets or 3 400 mg tablets.

Ibuprofen tablets should be taken after meals with water. The intervals between doses of the drug should not be less than four hours. Usually, expectant mothers are prescribed to use Ibuprofen for three to five days. In each case, the treatment regimen is drawn up individually. A woman expecting a child should not make adjustments to it on her own.

Ointment and suppositories with Ibuprofen

In addition to pills, pregnant women can use ointment and suppositories containing Ibuprofen. The ointment should be applied to sore joints, painful areas with a thin layer 2-3 times a day. In the third trimester, you cannot use it, just like pills.


Ibuprofen suppositories

Ibuprofen suppositories are made for children. One suppository contains only 60 mg of active ingredient. This dosage is too small for adults, therefore, suppositories for treatment are not prescribed for expectant mothers. If another dosage form was not found, and you need to take another dose of Ibuprofen, the pregnant woman can enter two suppositories at once.

Expectant mothers can also take children's syrup if the tablets are not in the medicine cabinet.

Side effects of the drug

Ibuprofen is a serious drug. When taken in pregnant women, the following adverse reactions may occur:

  • nausea, vomiting;
  • stomach pain, heartburn, bloating;
  • allergic reactions.

In some expectant mothers, this drug causes tinnitus, insomnia, double vision, and heart palpitations.


Side effect of ibuprofen - nausea

In warning about the risks to the fetus, scientists mean that Ibuprofen can cause

  • miscarriages, premature birth;
  • pulmonary hypertension of the fetus (the active substance of the drug can provoke premature closure of the ductus arteriosus, resulting in a sharp increase in pulmonary vascular resistance);
  • heart failure in the fetus.

In what situations are pregnant women unable to take Ibuprofen

Contraindications to taking Ibuprofen are:

  • third trimester;
  • individual intolerance to the components that make up the drug;
  • ulcers of the stomach and duodenum;
  • exacerbation of diseases of the gastrointestinal tract;
  • kidney or liver damage;
  • violation of blood clotting;
  • optic nerve pathology;
  • a history of coronary artery bypass grafting;
  • bronchial asthma.

Also, it is not advisable to take the medicine for women who have been diagnosed with diabetes mellitus.

It is important to know that Ibuprofen cannot be drunk at the same time as Aspirin, medicines that reduce blood clotting.