Pain is the most common reason for seeking medical attention. She often worries during pregnancy. Taking pain relievers, the expectant mother must be sure of its effectiveness and safety for the child. Among a fairly large selection of drugs, Ibuprofen is often preferred.
Use of Ibuprofen at different stages of pregnancy
Ibuprofen is a well-known and widely used non-hormonal anti-inflammatory drug, developed in 1962. It acts on the enzymes responsible for the production of prostaglandin, a substance that contributes to fever, pain and inflammation.
Ibuprofen has proven to be highly effective and well tolerated. It is included in the list of essential medicines compiled by the WHO, and in the list of vital and essential medicines of the Russian Federation. At the International Conference on the Use of this Substance in 2002, ibuprofen was characterized as follows:
Compared with paracetamol and acetylsalicylic acid, ibuprofen has less toxicity in overdose and, as a result, a wider therapeutic range.
Professor Élisabeth Autret – Leca (France)
http://www.rmj.ru/articles/pediatriya/K_40-letiyu_sozdaniya_ibuprofenaPervaya_meghdunarodnaya_konferenciya_po_primeneniyu_ibuprofena_v_pediatrii/#ixzz4HWbSrAlk
In the instructions for the drug, pregnancy is listed in the list of contraindications. But despite this, Ibuprofen is often recommended for expectant mothers as a good pain reliever. The doctor may only recommend Ibuprofen in the early stages of pregnancy. Starting from the third trimester, this substance is prohibited for use by expectant mothers.
Ibuprofen can cause premature closure of the ductus arteriosus, which supplies oxygenated blood to the still-dormant fetal lungs. Prostaglandins produced by the mother's body prevent intrauterine closure of the duct, and blocking their formation threatens the development of pathology.
Product safety assessed by the FDA
The US Food and Drug Administration (FDA) has categorized drugs into several categories based on how dangerous / safe they are for the developing fetus.
For Ibuprofen, the FDA has established category B (according to animal studies, the risk to the fetus was not identified, and there were no controlled studies with pregnant women, or there were side effects in animal trials, but the risk to the fetus was not confirmed in clinical studies in humans), and in the third trimester of pregnancy - D (there is good reason to consider the drug dangerous to the fetus).
Indications for use
Ibuprofen is a good remedy not only for eliminating the fever that accompanies the flu or colds, but also a proven medicine for different types of pain caused by:
- inflammation of the cartilage, tendons and joints of the bones and spine of a chronic nature;
- trauma, surgery and other reasons (this includes muscle, toothache and headache, migraines, neuralgia, painful menstruation).
Ibuprofen is used for symptomatic therapy; it reduces pain and inflammation, but does not address the cause of the problem.
Headache during pregnancy - video
Forms of drug release: what to choose and in which case
Manufacturers produce Ibuprofen in the following forms:
- pills;
- suspension;
- ointment;
- candles.
Comparative characteristics of tablets, suspensions, ointments and suppositories - table
| Release form | Amount of active substance | Recommendations for use for pregnant women |
| Pills | 200 and 400 mg in 1 tablet | It is forbidden to take ibuprofen in tablets and suspensions in the third trimester of pregnancy, and in the first and second trimester of pregnancy, its use must be discussed with a doctor. |
| Suspension | 100 mg in 5 ml | |
| Ointment | 50 mg in 1 g | The ointment is applied topically - mainly for problems with the musculoskeletal system. Despite this, it is not used in the third trimester, because the contraindication refers to the active substance, and not the form of drug intake. |
| Candles | 60 mg in 1 suppository | Suppositories are specially designed for children. This form of Ibuprofen is not prescribed for adults. |
The choice of the form of release largely depends on the reason that was the reason for the appointment of Ibuprofen. The most common are tablets and ointment (suspension and suppositories are more suitable for children in dosage and form of release). If the tablets can be prescribed for any indication, then doctors usually advise the ointment for women suffering from arthritis, osteoporosis, sciatica and myalgia.
Forms of release of Ibuprofen - photo gallery
Contraindications and side effects
Ibuprofen is contraindicated in the following cases:
- hypersensitivity to any of the ingredients that make up the drug;
- hypersensitivity to acetylsalicylic acid or other NSAIDs (non-steroidal anti-inflammatory drugs), including data on an attack of bronchial obstruction, rhinitis, urticaria after taking acetylsalicylic acid or other NSAIDs; complete or incomplete syndrome of intolerance to acetylsalicylic acid (rhinosinusitis, urticaria, polyps of the nasal mucosa, bronchial asthma);
- erosive and ulcerative diseases of the gastrointestinal tract in the acute stage (including peptic ulcer of the stomach and duodenum, Crohn's disease, ulcerative colitis);
- inflammatory bowel disease;
- hemophilia and other blood clotting disorders (including hypocoagulation), hemorrhagic diathesis;
- the period after coronary artery bypass grafting;
- gastrointestinal bleeding and intracranial hemorrhage;
- severe liver failure or active liver disease;
- severe renal failure, progressive kidney disease;
- confirmed hyperkalemia;
- pregnancy.
In addition, the drug should be used with caution in women with diabetes mellitus, lipid metabolism disorders, various diseases of the heart, circulatory and hematopoietic systems, liver, kidneys, stomach and intestines.
Taking Ibuprofen can result in a number of side effects.
- Irritation or dryness of the mucous membrane of the oropharynx, the formation of gums, stomatitis.
- Changes in the structure of the tissues lining the stomach associated with the use of NSAIDs, which is accompanied by heartburn, nausea and vomiting, constipation or diarrhea, bloating, abdominal pain, problems with appetite. In rare cases, ulcers may form on the gastrointestinal mucosa, which are prone to perforation and bleeding.
- Headache and dizziness, anxiety, nervousness and irritability, sleep problems, hyperexcitability or, conversely, drowsiness and depression, confusion and hallucinations, aseptic meningitis.
- Inflammatory diseases of the liver and pancreas.
- Rapid and labored breathing, bronchospasm.
- Hearing impairment, characterized by a decrease in its acuity, the appearance of noise or ringing in the ears.
- Vision problems associated with toxic damage to the optic nerve, manifested in the form of double vision, dryness, irritation, blurred vision. Edema of the eyelids and the outer mucous membrane of the eye of an allergic nature is possible.
- Increased blood pressure and heart rhythm disturbances, heart failure.
- Anemia, a decrease in the level of glucose, eosinophils, leukocytes, platelets and, as a result, deterioration of blood clotting.
- Inflammation of the kidneys of an allergic nature, cystitis, increased urine production, edema, acute renal failure, an increase in the creatinine level in the blood.
- Skin rash and itching, Quincke's edema, allergic rhinitis, anaphylactic shock and other reactions, fever, Stevens-Johnson or Lyell's syndrome.
- Increased perspiration.
Any adverse reaction affects not only the health and well-being of the woman, but also affects the baby, therefore, the appearance of the above symptoms after taking Ibuprofen is a reason to see a doctor and stop using the drug in the future.
Despite the large list of adverse reactions, the likelihood of their occurrence with Ibuprofen treatment is much lower than with other NSAIDs. Studies conducted in the UK indicate that if you follow the dosage and do not take more than 1200 mg of the substance per day, then the risk of complications from the drug is close to zero.
Drug interactions
- With the simultaneous administration of ibuprofen and aspirin, the effectiveness of the latter decreases and the likelihood of adverse reactions from the heart increases. The use of the drug simultaneously with other NSAIDs is not recommended.
- The effect of the substance on the level of platelets in the blood makes it unsafe to prescribe Ibuprofen with drugs that reduce blood clotting. Combined treatment with the drug and antibiotics from the cephalosporin group increases the likelihood of bleeding.
- Ethanol (or alcohol), found in some medicines, increases the risk of severe toxicity.
- Ibuprofen enhances the action of hypoglycemic drugs, including insulin, creating the likelihood of hypoglycemia.
Ibuprofen has other characteristics in relation to drug interactions that can affect the condition of a woman. The use of the drug must be agreed with the doctor. He will take into account all the risks and assess how safe this pain reliever is in each specific case.
Experts say that a single dose of Ibuprofen in the I and II trimester does not pose a danger to the health of the woman and the fetus.
Instructions for use
According to the instructions, the dose of Ibuprofen per day for adults should not exceed 1200 mg, i.e. 6 tablets of 200 mg each or 3 tablets of 400 mg of active ingredient. But for pregnant women, it is prescribed for a single dose, and not as a means of constant therapy. Despite the relative safety of ibuprofen in the first and second trimesters, we must not forget that the substance easily passes the placental barrier, and its effect on the fetus and the course of pregnancy has not been thoroughly studied.
Pregnant women cannot take ibuprofen for a long time. This drug has only a symptomatic effect and is used when absolutely necessary when safer methods of solving the problem have been ineffective.
What can replace Ibuprofen
Ibuprofen is not the only pain management agent. It has both analogues in terms of the active substance and preparations similar in their effect.
There are a lot of ibuprofen-based drugs. The most famous analogs, their dosage forms and dosages are given below.
Complete analogues of the drug - table
Ibuprofen's analogs - photo gallery
Ibufen is allowed in syrup and capsules 
MIG is a German-made drug 
Burana tablets can be bought in different dosages 
Nurofen is a medicine of the English Pharmaceutical Company 
Faspik - an Italian drug based on ibuprofen
In addition to ibuprofen, pregnant women are allowed other substances that have a similar effect on the body.
Drugs that can replace Ibuprofen - table
| Drug name | Release form | Active substance | Contraindications | Application during pregnancy |
| Paracetamol |
| Paracetamol |
| Although the studies have not established the negative effect of paracetamol on the unborn child, before using it in pregnant women, it is necessary to compare the expected benefits of therapy for the mother and the potential danger to the fetus. |
| Panadol |
| Paracetamol | Hypersensitivity to the components of the drug. | Panadol is used with caution and only under the supervision of a physician without exceeding the dosage acceptable for pregnant women. |
| No-Shpa |
| Drotaverine hydrochloride |
| Drotaverine is not toxic to the fetus, does not have a negative effect on the formation of the fetus and has no adverse effect on the course of pregnancy. However, in the case when you cannot do without the use of No-Shpa, pregnant women should be careful. The drug is used only if the intended benefit to the woman is higher than the potential risk to the fetus. | Panadol is a foreign drug that has proven itself in many countries around the world.
Any doctor, prescribing any remedy for a pregnant woman, thinks first of all about not harming the baby. And a question of this nature is not easy to solve.
One of those rare medicines which consumption is allowed during pregnancy- this is Ibuprofen.
Quite a bit about the drug itself. It has positive properties. Ibuprofen can be considered undoubtedly one of the best and most correct choices in pregnancy.
The drug is not considered an anticoagulant. This means that it will not cause and, moreover, cannot represent.
The expectant parent should pay close attention to the use of this agent during lactation. The use of ibuprofen while breastfeeding is also possible, because its constituent elements in no way affect the secretion and the very quality of breast milk.
Composition of the medicine
Ibuprofen is a non-hormonal (non-steroidal) anti-inflammatory drug. It is a mild antipyretic and anti-inflammatory analgesic.
Ibuprofen is consumed in different pharmaceutical forms - from a tablet to an ointment, it is imperative to remember that contraindications usually refer to the drug itself, but not to its form of manufacture.
Selection of forms of production:
- gel for external use;
- pills;
- suspension for oral administration;
- suppositories for use in the rectum.
There are children's release types.
Indications for use
Ibuprofen in the medical field is considered a non-steroidal and anti-inflammatory agent, which has anti-inflammatory and analgesic properties, as well as antipyretic effects.
Ibuprofen is used to treat, for example, ailments such as adnexitis and sciatica, bursitis and gout, neuralgia and proctitis, and a number of others.
A similar drug has also found its use against, muscle and. And if someone has a respiratory problem, then Ibuprofen can help cure that too.
Positive effects on the body
Overall, this medicine is one of the best antipyretic drugs for a pregnant woman.
It should be emphasized that the danger of a single use of Ibuprofen during pregnancy is practically zero, which certainly makes it the drug of choice for the relief of very acute pain or fever.
Why is the drug dangerous (and is it dangerous?) For pregnant women?
Contraindications for use
How will the medicine affect the development of the embryo? Yes, problems can appear. Before using Ibuprofen, you should definitely consult with your doctors, since the medicine can be contraindicated for the patient for various reasons.
Important contraindications include erosion or ulcers of the gastrointestinal tract at the stage of exacerbation, various disorders of hematopoiesis, the presence of, so to speak, an "aspirin triad" (difficult or generally intolerance to aspirin), diagnosis of bronchial asthma and nasal polyps, significant dysfunctions kidney and liver.
Ibuprofen can cause, and with an increased degree of likelihood -. It can negatively affect the coagulation system of the parent and increase the risk of bleeding.
Side effects
Side effects include hearing loss, that is, ringing or tinnitus, anxiety and nervous conditions, and hallucination, heart failure and blurred vision or double vision, dryness and irritation of the eyes, in addition, abnormalities in labor.
Dosage and duration of admission
It is not recommended to exceed a daily dose of more than 3200 mg (these are 16 tablets), you cannot consume more than 1000 mg per day without consulting a doctor.
The tablets are washed down with one glass (200 ml) of water. Desirable take with food.
Prescribing a dose of 3200 mg is otherwise better than a dose of 2400 mg, although in many patients both doses have the same effect.
The rate should be adjusted based on the patient's response. With a febrile syndrome of various origins, pain syndrome, one or two tablets at once or in 3 or 4 doses during the day, if necessary.
The maximum dose per day is 40 mg / kg of body weight.
Duration of treatment is this: if, when using the medicine for 5 days, the pain syndrome or for 3 days, the fever still persists or intensifies, it is necessary to stop treatment and go to the doctor.
We must not forget that long-term use of Ibuprofen can exacerbate long-healed gastritis, peptic ulcer in the stomach and duodenum, in addition, it can provoke various types of gastrointestinal bleeding, especially in people who have had episodes of such bleeding in the past.
Features of the drug
In the first trimester
Many scientific experiments have confirmed that the drug has virtually no negative effect on the development of the embryo in the womb, if taken during the first or second trimester, however, in the first trimester, the danger is still higher, because the organs and systems of the embryo are just being formed.
Isolated cases of consumption are unlikely to harm a woman's health, especially at the very beginning of pregnancy. But with frequent consumption, especially in large dosages, everything can end badly.
In the second and third trimesters
During the second and third trimester, this drug during pregnancy can be used in cases where the danger of using the drug is less than the danger of the disease.
Like numerous other drugs, doctors do not recommend using Ibuprofen for pregnant women who are already on the deadline.
And more precisely, from the 28th week, it is simply contraindicated.
This drug is used with caution in the later stages due to the fact that it can suppress the production of prostaglandins, and thus affect the contraction of the uterus, as well as cervical maturation and generic dominance.
Thus, labor can be impaired, in addition, the risk of premature birth or overmaturity increases.
Effective analogues. What can replace the drug?
Currently, there are no structural analogues of Ibuprofen with exactly the same active element.
If necessary, you should consult a doctor in order to select a replacement drug with similar properties, but with a different active ingredient.
These include:
- Dolgit and Brufen;
- and MIL;
- Ibufen and Deblock;
- Burana and Faspik;
- Ibuprom and Ibusan;
- Nurofen forte and Solpaflex;
- Ibutop and Pedea.
And finally, we will remind only one, but the golden rule for any pregnant woman: always be sure to consult with your doctors if you are going to use any drug.
Try to avoid taking any medication and never self-medicate.
Every girl dreams of becoming a mother. The period of pregnancy in her life is associated with something: amazing, unforgettable, amazing. But, do not forget that it was at this time that a woman is incredibly responsible not only for herself, but also for the unborn child. Based on this, pregnant women need to be very careful and try to avoid negative external influences. A woman who gives birth not for the first time knows that immunity weakens and you can catch a cold any day, even if you are a little blown away. That is why it is important to know how to treat a cold.
Action of ibuprofen during pregnancy
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID / NSAID) that belongs to the group of propionic acid derivatives. The drug is a bright white powdery crystals, which is practically insoluble in water, but perfectly soluble in ethanol or acetone. Release form of the drug: tablets, syrup, gel, cream, ointment.
Ibuprofen has the following properties:
- Relieves inflammation, pain, eliminates fever.
- Stops or eliminates the biosynthesis of prostaglandins E and F, which provoke contraction of the muscle tissue of the uterus and gastrointestinal tract.
- It stimulates the production of special proteins that are secreted by the body when a viral infection - interferons - gets into it, therefore it perfectly supports the immune system and protects the body.
- The properties of the substance that eliminate pain and heat are more pronounced than the properties that eliminate inflammation. But ibuprofen works better than aspirin and amidopyrine, and has fewer negative effects than more NSAIDs.
Ibuprofen is on the WHO List of Essential Medicines. The application is practiced by doctors from all over the world.
Is ibuprofen possible during pregnancy: when is it prescribed
Pregnancy is not without complications in the majority of the fairer sex. However, no person is 100% healthy and everyone can catch a cold. And the health of the child also depends on the condition of the woman during gestation, therefore, the therapy of many pathologies is performed by doctors with the help of the most effective medication that is not harmful to the baby developing in the womb. However, one cannot but say that treatment with serious medications is carried out only in the most severe cases, when the potential harm to the child is less than that caused to the health of a pregnant woman.
So, Ibuprofen and medications with it are prescribed:
- To stop acute pain, as well as for the treatment of diseases of the musculoskeletal system: arthrosis, arthritis, inflammatory processes resulting from injury.
- For headaches and pain in the teeth, as a pain reliever.
- At high temperatures as a heat reliever.
- During the period of acute respiratory infections, to maintain the immune system in the fight against pathologies and to relieve inflammation in the ears, nasopharynx, larynx.
- As an alternative to antibacterial agents for mild disease.
- As a replacement for Aspirin, because Ibuprofen does not inhibit blood clotting and does not provoke bleeding.
Attention! Self-administration of drugs is contraindicated during pregnancy.
Is Ibuprofen used during early pregnancy?
Doctors often allow drinking or using Ibuprofen topically when the first and second trimester of pregnancy is in progress. Because it has been proven that the drug cannot have any negative impact on the development of the baby during this period. But, very careful use of Ibuprofen in any form should be in the very early stages of bearing a child. In the first twelve weeks, the drug can be dangerous for the baby, in principle, like any other medication (MIG, Ibuklin, Nurofen, Ibufen, etc.).
During this period, all:
- Fabrics;
- Systems;
- Organs of the child.
Impact on a developing small organism chem. substances is highly undesirable. Studies have been carried out and scientists have found that Ibuprofen and other medications of the NSAID class increase the risk of miscarriage by 2.4 times. Of the more than 4500 miscarriages studied, 352 (7.5%) women were treated with non-aspirin NSAIDs.
Experts have come to the conclusion that the use of any dosage of NSAIDs for women in the early stages of gestation greatly increases the risk of spontaneous abortion.
In the third trimester (after 28 weeks), Ibuprofen is not recommended. The medicine has a direct effect on the process of uterine contraction, cervical ripening, childbirth. There is a risk of miscarriage or premature birth.
Ibuprofen ointment during pregnancy: 1 trimester
It is not uncommon for a pregnant woman to suffer from a joint disease and in the first trimester the pathology worsens, or the woman injured the ligaments. However, there is no need to drink pills often; it is better to replace them with external topical agents.
Today, there is almost no difference between ointments and gels based on the main active ingredient.
They do not differ significantly in the speed of absorption and in the constituent components. After application to the skin, the therapeutic effect occurs as soon as the active substance is absorbed.
Having penetrated the inflamed area, the ointment:
- Affects the painful area;
- Reduces pain syndrome quickly;
- Eases the condition of a woman.
But some part of the drug still enters the woman's bloodstream. Ibuprofen is readily absorbed into the placenta. Although the concentration of the active substance in the blood for external use is several times less than if you drink a couple of tablets, this should be taken into account. We must not forget that if the drug in the 1st trimester is relatively safe for a developing baby, it should not be abused, one way or another. A pregnant woman may face a common side effect of NSAIDs - a negative effect on the gastric mucosa. And this can lead to the development of gastritis or even ulcers.
In this case, you should rebuild the diet and follow a special diet.
In the early stages, a pregnant woman should eat, which is said for two. It can be quite difficult to follow such a diet for stomach diseases. This negative result usually comes from taking tablets or suspensions. Parenteral administration (injections) are the least dangerous in this regard, but after them inflammation may develop at the site of the needle entry. A sore stomach or inflammation at the injection site can lead to the appointment of other medications that are no longer as safe for the child in the early stages than Ibuprofen.
As statistics show, the appointment of Ibuprofen for systemic use is required in approximately 5% of all carrying a child registered in the clinic. Therefore, despite the fact that the drug is seemingly harmless, in the first trimester it should be used only according to indications, as prescribed by the attending physician.
2nd trimester: Ibuprofen during pregnancy
It is possible to use the drug in the 2nd trimester only as directed by a doctor, but the drug can cause side effects.
The reaction of a pregnant woman's body to Ibuprofen may be as follows:
- Nausea and vomiting;
- Pain in the gastrointestinal tract;
- Bleeding;
- Allergy of various manifestations;
- Insomnia;
- Visual impairment;
- Instability of the psyche, irritability, apathy;
- Hallucinations (rarely, in case of overdose);
- Feeling of lack of oxygen, rapid breathing.
If you take the medicine once, you can hardly be afraid of side effects, but during therapy with a course, they can appear at any time. The longer the course of therapy with Ibuprofen lasts, the greater the likelihood of side effects.
3rd trimester: Ibuprofen during pregnancy
Particularly dangerous for the development of the child is the use of the medication during gestation in the third trimester. The time when it is absolutely impossible to use Ibuprofen is the 3rd trimester. All drug studies show a strong effect of this active ingredient on the baby. At this stage of pregnancy, it is better to avoid all medications altogether, since most of the drugs can penetrate into the blood of the expectant mother, and therefore through the placenta to the baby.
What is possible to replace the drug with? Ibuprofen belongs to the group of NSAID medications, which also includes other active ingredients. The safest of these is paracetamol. Among the medicines that do not have the strongest effect on the fetus, it is worth mentioning Paracetamol and Papaverine.
These are medications such as:
- No-Shpa;
- Panadol;
- Drotaverinum.
They have a mild effect and will help relieve pain of moderate intensity, as well as reduce the manifestations of the inflammatory process and bring down high temperatures. Temperature is very harmful when carrying a child, sometimes even more than the medications themselves. Sometimes doctors do not recommend taking medications at all, but advise using alternative medicine methods. But, if the catarrhal pathology is serious and you cannot do without the help of medicines, then the doctor prescribes the most sparing therapy for the mother and child.
How to use Ibuprofen ointment for pregnant women (video)
Pregnancy is a special condition in a woman's life. It is full of joyful anticipation, but at the same time you have to worry a lot. One of the main fears is to get sick during this period, because it is not known how the disease will affect the child, and the possibilities of drug therapy are very limited.
Most often, women are faced with acute respiratory viral infections and fever, pains of various origins and intensities, and some other diseases. Doctors often recommend taking ibuprofen. But can this be done, and how safe is it?
What is Ibuprofen?
Ibuprofen is a non-steroidal anti-inflammatory drug, a relatively safe and effective pain reliever and antipyretic drug. It gradually inhibits the main enzyme of the metabolism of arachidonic acid, which is a precursor of prostaglandins, which trigger and regulate the process of inflammation, pain and fever. This means that the drug not only relieves symptoms such as pain and fever, but also eliminates the inflammation itself.
In addition, there is evidence of the ability of ibuprofen to stimulate the production of interferon by the cells of the human body. The medicine is able to activate the body's defenses and increase its resistance to disease.
Indications and contraindications for use
Most often, ibuprofen is recommended for the treatment of ankylosing spondylitis, deforming osteoarthritis, and various rheumatoid diseases. With rheumatoid arthritis, the greatest effect can be achieved when taking the drug in the initial stages, even before the onset of serious changes in the joints. In terms of its effect, it is slightly inferior to indomethacin and ortofen, but it is better tolerated.
In recent years, the popularity of ibuprofen has grown sharply as an antipyretic used for the symptomatic treatment of fever in infectious diseases.
It is also used for pain after trauma and migraine, toothache and after surgery. The medicine is allowed even for newborns and pregnant women, moreover, sometimes it is taken in childbirth to relieve pain and slow down labor.
The main contraindications for the use of ibuprofen:
- Hypersensitivity to the drug;
- Erosive diseases of the gastrointestinal tract;
- Blood clotting disorders;
- "Aspirin" asthma.
Also, caution is needed when using ibuprofen in patients with liver disease, kidney disease, inflammatory diseases of the gastrointestinal tract. Taking the drug by children under one year old and pregnant women requires prior consultation with a doctor.
For a long time, aspirin remained the drug of choice for pain. But recent studies have shown that it has a teratogenic effect. Today, paracetamol is considered the safest drug, while ibuprofen is the second choice.
There is no reliable evidence that taking this medication in the first or second trimester of pregnancy can harm the baby or woman. In the third trimester, its use is limited due to the increased risk of such effects.
Mode of application
Ibuprofen is taken orally, always after meals, to reduce the negative effects on the gastrointestinal tract. During pregnancy, before treatment, it is imperative to consult with your doctor about choosing a safe dose.
If this is not possible, you need to start with the minimum. If you have to take the drug regularly, for example, for the treatment of rheumatoid arthritis, the woman should be under constant medical supervision and control.
Side effects
Sometimes taking ibuprofen leads to the development of side effects. It can cause digestive problems such as vomiting, heartburn, and stomach pain and bloating, to name a few. Also sometimes there are headaches, insomnia and even hallucinations in extremely rare cases.
Hearing and vision impairment, development and increase in blood pressure are possible. Disorders in the functioning of the kidneys and the hematopoietic system are occasionally observed. With hypersensitivity, itching, allergic rhinitis, Quincke's edema, etc. may occur.
The simultaneous use of ibuprofen with other NSAIDs, anticoagulants and thrombolytics, cefoperazone, cyclosporine and some other drugs is prohibited.
Regular use of large doses of medication during pregnancy can threaten:
- A decrease in the amount of amniotic fluid;
- Violation of the development of the heart of the fetus;
- Inhibition of labor.
Therefore, only a doctor can decide what is more dangerous for the mother and fetus, the symptoms of the disease or the effect of the drug.
Some researchers argue that ibuprofen in the first trimester can provoke abortion, and regular use of the drug in the early stages leads to the formation of a "cleft palate" in the fetus and abdominal wall defects. But there is no solid evidence for these ideas - these are nothing more than assumptions.
conclusions
Ibuprofen is one of the safest non-steroidal anti-inflammatory drugs approved for use during pregnancy. Its one-time reception in the early stages carries almost no risks. If longer treatment is required or use in the third trimester, this should be done under the supervision of doctors.
A woman during her pregnancy should be responsible for her own health and for the life of her unborn baby. But a period of 9 months creates a lot of difficulties for a woman. She becomes vulnerable to the most unexpected illnesses, which are accompanied by pain, fever, inflammation. Therefore, she has a natural question, how to get rid of the disease without harming the baby? Today, there are many drugs that are relatively safe during gestation with a good analgesic effect. One of them is Ibuprofen. But this remedy can both help and harm, so let's figure out if Ibuprofen is possible during pregnancy.
Ibuprofen is a popular non-hormonal drug with a pronounced analgesic effect. It was developed 60 years ago, and over a long period of use has proven its effectiveness. The main effect of the drug is to affect the enzymes that are responsible for the synthesis of prostaglandins - compounds that provoke pain, fever, and inflammation.
In addition to its therapeutic effect, Ibuprofen has shown itself to be a drug that is well tolerated by most patients. It occupies one of the leading positions in the list of important drugs, since it has less toxicity compared to similar drugs.
Important! To reduce pain and inflammation in muscles and joints, Ibuprofen Gel is preferred during pregnancy. In this form, it is practically not absorbed into the bloodstream and the risk of harming the fetus is minimal.
Prescribing Ibuprofen in early pregnancy
Is it safe to take Ibuprofen during the gestational period is an urgent question for all women who are looking for an effective and reliable drug to isolate the focus of inflammation and pain. Since pregnancy is a contraindication to use in the instructions, the answer to this important question remains ambiguous.
But a special note in the annotation that in the 1st and 2nd trimester the use of Ibuprofen is permissible if the benefit exceeds the risk of complications, leaves a narrow corridor for the appointment of Ibuprofen in some cases.
The appointment of Ibuprofen during pregnancy in the 1st trimester is rather an exception to the rule and may be one-time. For example, with a sharp increase in body temperature or severe pain.
In all other cases, where long-term anti-inflammatory therapy is required, alternative solutions should be considered. Such restrictions are caused by the fact that the active substance of the drug - ibuprofen - can negatively affect the laying of organs and systems of the embryo, as well as cause a threat of miscarriage.
The use of Ibuprofen during pregnancy in the 2nd trimester no longer has a toxic effect on the fetus, since it is strong enough. But the appointment of this drug must be justified by the serious condition of the woman.
If the pregnancy is proceeding with violations, or there is a threat of termination, then it is advisable to refuse Ibuprofen. And the treatment of infectious diseases is carried out with herbal preparations and recipes of traditional medicine.
On a note! Studies have shown that taking Ibuprofen at the planning stage or in the first days after conception makes it difficult for the normal implantation of the ovum and can provoke a miscarriage.
Taking Ibuprofen late in pregnancy
It is strictly forbidden to take ibuprofen during pregnancy in the 3rd trimester. This is due to the property of the drug to suspend the synthesis of prostaglandin, which stimulates the myometrium. Its deficiency can contribute to a decrease in amniotic fluid, prolonged pregnancy and prolonged delivery.
In addition, prolonged use of Ibuprofen in the late stages often leads to damage to the baby's cardiovascular system, and in some cases, to his intrauterine death. The fetus can be diagnosed with cardiopulmonary toxicity, renal failure. And a woman in labor increases the risk of postpartum hemorrhage.
Ibuprofen: instructions for pregnancy
Ibuprofen instructions must be strictly followed during pregnancy. According to the information posted in it, this agent is used as an antipyretic and anti-inflammatory drug. Ibuprofen is produced in convenient forms, which makes its use as comfortable and effective as possible.
Composition and medicinal varieties of Ibuprofen
The active substance of the drug is ibuprofen. Its concentration, as well as the list of excipients, is determined by the dosage form of Ibuprofen in the form of tablets, gel, suppositories, syrup.
- Ibuprofen tablets - during pregnancy are prescribed in low doses of 200-400 ml. They contain corn starch, cellulose, silicon dioxide. Pills are available in round shape, white, with a convex surface. The therapeutic dose is concentrated in the blood 1-2 hours after administration. The drug is rapidly excreted by the kidneys.
- Ibuprofen suspension - dosage form for children. Contains ibuprofen, as well as orange flavor, xanthine gum, glycerol, polysorbate. The maximum daily dose for pregnant women is 2.4 g. It is the safest form of ibuprofen for early pregnancy.
- Ibuprofen suppositories is another form of the drug for children that is acceptable for women during pregnancy. One suppository contains 60 ml of ibuprofen and 500 ml of solid fat. Applied rectally.
- Ibuprofen ointment - during pregnancy, it is used for external application for muscle or articular pain syndrome of rheumatic origin or as a result of injury. Contains 50 ml of active substance in 1 g of the preparation. Additionally, the preparation contains carbopol, polyethylene glycol, methylparaben, alcohol. It is produced in the form of a soft, colorless mass with a characteristic odor.
Indications for the appointment of Ibuprofen during pregnancy
The reason for the appointment of Ibuprofen during pregnancy can be the following diseases and conditions of a woman:
- Attacks of headache or toothache.
- Neuralgia.
- Pain localized in the musculoskeletal center.
- Colds, flu.
- Inflammatory diseases (gout, rheumatism, osteoporosis).
Ibuprofen ointment is indicated for:
- Inflammation of tendons, joints, or muscles resulting from trauma (eg, sprains, bruises).
- Exacerbation of rheumatic disease.
- Radiculitis, lumbago.
- Swelling of the upper tissues near the focus of inflammation.
Important! In obstetric practice, Ibuprofen is used in emergency cases when it is required to suspend labor.
Contraindications and side effects of Ibuprofen
Ibuprofen, in addition to its potential danger to pregnancy, has the ability to negatively affect other organs. Therefore, direct contraindications to its appointment are:
- Intolerance to the active substance or other components.
- Establishment of an asthmatic attack, angioedema, angioedema after taking ibuprofen or aspirin in the history of a pregnant woman.
- Peptic ulcer of the stomach.
- Perforation of the intestinal wall in the past after taking non-steroidal drugs, including ibuprofen.
- Severe pathology of the heart, kidneys or liver.
- Third trimester of pregnancy.
- Hemophilia and hemorrhagic diathesis.
- Diagnosed hyperkalemia.
Ibuprofen in the form of an ointment is contraindicated for skin diseases (eczema, dermatosis), purulent wounds or damage to the mucous membranes.
Special attention should be paid to adverse reactions after taking Ibuprofen. Their list is so large that the desire to take this remedy during pregnancy is sharply reduced.
What may worry a woman after treatment with Ibuprofen:
- Violation of hematopoiesis: agranulocytosis, anemia, bleeding, hemorrhagic hematomas.
- Throat affection: ulcers, pain, irritation.
- Immunity disorders: urticaria, swelling (tongue, mouth, eyelids), anaphylactic shock, anaphylaxis, bronchospasm, asthmatic attack, epidermal necrolysis.
- Malfunctions of the nervous system: aseptic form of meningitis, migraine.
- Cardiovascular pathologies: heart failure, myocardial infarction, hypertension.
- Dysfunction of the gastrointestinal tract: nausea, pain syndrome, bloating, internal bleeding, exacerbation of Crohn's disease, colitis, vomiting.
- Sensory disturbances: hearing impairment, damage to the optic nerve.
In addition to these adverse reactions, women may develop renal failure, a decrease in hemoglobin levels, and ulcerative stomatitis. And with the external application of Ibuprofen ointment, redness, rash, itching may appear on the skin.
Important! In women with lupus erythematosus, taking even one ibuprofen tablet for a headache during pregnancy can cause the development of aseptic meningitis.
Interaction of Ibuprofen with other drugs
- Aspirin: The combination of the two increases the side effects of Ibuprofen.
- Warfarin and other anticoagulants: Ibuprofen significantly enhances the effect of these drugs.
- Corticosteroids: the risk of internal bleeding increases.
- Cardiac glycosides: cardiac function may deteriorate, glomerular renal infiltration may decrease.
- Quinolic antibiotics: there is a risk of seizures.
Important! It is unacceptable to take other non-steroidal anti-inflammatory drugs together with Ibuprofen.
Dosage and duration of treatment, Ibuprofen overdose
Ibuprofen can only be taken in short courses of up to 5 days. The tablets are swallowed without damaging the membrane. It is advisable to drink the pills with plenty of plain water.
During pregnancy, it is desirable to use the lowest dose while maintaining the therapeutic effect. For adults weighing more than 30 kg, the daily dose is not more than 1200 ml. It is divided into three doses of 400 ml.
Ibuprofen ointment is applied to a clean area of the skin, avoiding contact with mucous membranes. A small amount of the drug is applied to the skin and rubbed gently. No more than 4 rubbing is allowed per day. The duration of treatment can be from three days to 2 weeks.
The dosage and duration of taking Ibuprofen in the form of suppositories and syrup is set by the doctor on an individual basis, taking into account the woman's weight.
Important! Long-term use of ibuprofen during pregnancy can cause fluid retention and hypertension. Therefore, all women who have the prerequisites for the development of gestosis should avoid this remedy.
If the dosage of Ibuprofen has been exceeded, the woman may experience complications that require medical attention.
Overdose signs:
- Severe nausea.
- Abdominal pain.
- Noise in ears.
- Disorientation in space.
- Brown feces (with internal bleeding).
- Choking attack.
If the following symptoms appear, you should immediately consult a doctor.
Effective and safe Ibuprofen analogues
On the basis of the substance ibuprofen, there are many analogues of this drug, both domestic and foreign. They differ in dosage, release form, additional components.
Among the most effective analogues of Ibuprofen are:
- Nurofen.
- Arviprox.
- No pain.
- Arofen.
- Beaufen.
- Ibuprex.
- Ibun Forte
- Eurofast.
- Ibufen.
- Ivalgin and others.
Important! Replacing Ibuprofen with its analogue during pregnancy should be carried out after consulting a doctor.
Ibuprofen during pregnancy - reviews
For pregnant women, ibuprofen is often a real panacea. The girls speak with gratitude about this drug, telling how it helped to endure severe toothache, exacerbation of rheumatism, migraine attacks. But most of the women were able to survive with its help a serious complication during pregnancy - symphysitis. This pathology is accompanied by indomitable pain during movement, which is caused by inflammation in the pubic joint.
There are also many reviews that talk about various adverse reactions in the form of vomiting, nausea, stomach pain, allergies. But individual intolerance and non-compliance with the dosage in these cases cannot be ruled out.
If you need to take Ibuprofen during pregnancy, you need to be careful. In non-critical situations, it is best to stick to the dosage for children. Of course, a one-time intake of Ibuprofen for toothache during pregnancy is unlikely to lead to serious complications, but there is no need to take risks in a "special" position.
